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KMID : 0378019820250070139
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New Medical Journal
1982 Volume.25 No. 7 p.139 ~ p.143
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A Clinical Evaluation of Cefadroxil in Pneumonia
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金三溶/Kim, Sam Yong
朴國太/金仙英/辛榮泰/Park, Kuck Tae/Kim, Sun Young/Shin, Young Tai
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Abstract
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Cefadroxil, a new oral cephalosporin antibiotic which is almost completely absorbed from gastrointestinal tract, uneffected by the presence of food in stomach, has a serum half-life approximately twice that of other cephalosporins, was evaluated in the treatment of 15 patients with pneumonia who were admitted to the Dept, of Int. Med., Chung Nam National University Hospital from July, 1981 to January, 1982.
In the 15 cases, 9 cases had underlying diseases; 2 cases of pulmonary tuberculosis, 2 cases of congestive heart failure, 1 case respectively of lung cancer, chronic bronchitis, diabetes mellitus, liver cirrhosis and cerebral hemorrhage.
Identified bacteriae in the 15 cases were; Streptococcus pneumoniae 9 cases, Staphylococcus aureus 3 cases, Klebsiella pneumoniae 2 cases, Haemophilus influenzae 1 case.
Results of treatment in the 15 cases were; cure 13 cases, partial response I case and no response 1 case. The response rate was 93.3%. The two organisms persisted on cefadroxil treatment were Streptococcus pneumoniae and Haemophilus influenzae. As of side effects, skin rash and pururitus in the one case and gastric cramp in one case were observed.
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